Strain Information | |
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Image | |
BRC No. | RBRC09236 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6.ICR-Tg(CDKN2A-luc)53Eiha/EihaRbrc |
Former Common name | p16-luc(B6), B6-p16-luc Tg, Human p16-luc mouse, p16-luc(Acc. No. CDB0416T-53)(B6) |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Eiji Hara, The Cancer Institute, Japanese Foundation for Cancer Research. The transgene was injected into the pronuclei of ICR fertilized eggs. The mutant mice were backcrossed to C57BL/6. |
Strain description | human p16-luciferase transgenic mice. |
Colony maintenance | Carrier x Noncarrier [C57BL/6JJcl] |
References | J. Cell Biol., 186, 393-407 (2009). 19667129 |
Health Report | |
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Examination Date / Room / Rack | 2024/02/19Room:4-ARack:G 2023/11/20Room:4-ARack:G 2023/08/21Room:4-ARack:G 2023/05/22Room:4-ARack:G 2023/03/22Room:4-ARack:G 2023/02/20Room:4-ARack:G 2022/11/21Room:4-ARack:G 2022/08/22Room:4-ARack:G 2022/05/23Room:4-ARack:G 2022/05/23Room:4-ARack:G |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lucluciferaseUNluchuman CDKN2A promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)UN |
Ordering Information | |
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Donor DNA | Human CDKN2A (p16ink4) genomic DNA, Firefly luciferase cDNA, E. coli neo |
Research application | Cell Biology Research |
Specific Term and Conditions | (1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Eiji Hara, The Cancer Institute of Japanese Foundation for Cancer Research, E-mail:eiji.hara@jfcr.or.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0416T-53 and Web. Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Cell Biol. 2009 186(3):393-407.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
Depositor | RIKEN CDB (RIKEN CDB) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved sperm (within 1 month) Live mouse (1 to 3 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |