Strain Data Sheet
Data update: Aug 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC09238  
Type TransgeneCartagena  
Species Mus musculus  
Strain name C57BL/6-Tg(CAG-CCND1)14Hzi  
Former Common name D1b14F, B6-CAG-CCND1 Tg#14  
H-2 Haplotype No Data  
Background strain C57BL/6JJcl  
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Hirokazu Inoue, Shiga University of Medical Science and Gen Kondoh, Institute for Frontier Medical Science. The transgene was injected into the pronuclei of C57BL/6 fertilized eggs.  
Strain description Cyclin D1b transgenic mice in which the human cyclin D1b transgene was driven by a pCAGGS promoter. Tg females develop rectal tumoers within 4 to 12 months after birth (female: 60%, male: 4%). The transgene was inserted into the intron region in chromosome 7 (7qA1).  
Colony maintenance Carrier x Noncarrier [C57BL/6JJcl]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol FLAG  
Symbol name FLAG tag (synthetic)  
Chromosome 7  
Common name No Data  
Symbol description No Data  
Promoter CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)  
 2 Symbol CCND1  
Symbol name cyclin D1 (human)  
Chromosome 7  
Common name No Data  
Symbol description No Data  
Research applications Cancer Research,
Cell Biology Research,
Mouse Models for Human Disease  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.  
Additional information
 1 No Data  
Depositor Inoue, Hirokazu (Shiga University of Medical Science)  Inoue, Hirokazu 
Strain Status /
(Expected delivery)

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