Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jul 19, 2019
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RBRC No. RBRC09248  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name CHe.129-Trp53<tm1Brd>  
Former Common name BALB/c-Trp53 KO, BALB-p53 KO  
H-2 Haplotype No Data  
ES cell line AB1 [129S7/SvEvBrd-Hprt<+>]  
Background strain BALB/cHeA  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Peter Demant, The Netherlands Cancer Institute to Osaka Prefecture University. The mutant mice were backcrossed to BALB/cHeA over 10 times.  
Strain description Trp53 knockout mice, BALB/cHeA background. Homozygous mutant mice can grow after birth, but die within a few months after birth due to the development of tumors.  
Colony maintenance Heterozygote x Wild-type [or Crossing to BALB/cHeAHiOpu (RBRC09247)]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Trp53  
Symbol name transformation related protein 53  
Chromosome 11  
Common name No Data  
Symbol description No Data  
Promoter mouse polymerase II promoter  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 11  
Common name No Data  
Symbol description No Data  
References

  


Research applications Cancer Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Mori, Nobuko (Osaka Prefecture University)  Mori, Nobuko 
Strain Status /
Availability
(Expected delivery)

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