Strain Information | |
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Image | |
BRC No. | RBRC09393 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6-Kcnj11<tm2Sse> |
Former Common name | Kir6.2-flox |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Susumu Seino, Kobe University Graduate School of Medicine. ES cells derived from C57BL/6 were used. C57BL/6 genetic background. |
Strain description | |
Colony maintenance | |
References | J. Clin. Invest., 130(12):6639-6655 (2020). 33196462 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Kcnj11potassium inwardly rectifying channel, subfamily J, member 117Kcnj11<tm2Sse>targeted mutation 2, Susumu SeinoKir6.2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site7Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site7Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (Bovine)7GH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)7mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | Phage P1 loxP sites, Yeast FRT (flippase recombination target) sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin resistance gene, Bovine Growth hormone poly A signal, mouse Kcnj11 genomic DNA |
Research application | Cre/loxP system Endocrine Deficiency Research FLP/frt system Neurobiology Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Susumu Seino (Kobe University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |