Strain Information | |
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Image | |
BRC No. | RBRC09595 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129P2-Keap1<tm2Mym> |
Former Common name | Keap1 flox |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Biochem. Biophys. Res. Commun., 339, 79-88 (2006). 16293230 Mol Cell Biol., 30, 3016-3026 (2010). 20404090 |
Health Report | |
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Examination Date / Room / Rack | 2023/08/28Room:4-BRack:I 2023/05/29Room:4-BRack:I 2023/02/27Room:4-BRack:I 2022/11/29Room:4-BRack:I 2022/08/29Room:4-BRack:I 2022/05/31Room:4-BRack:I |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EGFPEnhanced Green Fluorescent Protein (Aequorea victoria)9EGFP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP9loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP9loxP |
Ordering Information | |
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Donor DNA | Phage P1 LoxP sites, Splicing accepter, jellyfish EGFP cDNA, mouse Keap1 genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem Biophys Res Commun., 339, 79-88 (2006)., Mol Cell Biol., 30, 3016-3026 (2010).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Masayuki Yamamoto (Tohoku University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Vallelian F, Buzzi RM, Pfefferlé M, Yalamanoglu A, Dubach IL, Wassmer A, Gentinetta T, Hansen K, Humar R, Schulthess N, Schaer CA, Schaer DJ. Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia. Cell Death Differ 29(8) 1450-1465(2022) 35031770 |