Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Aug 20, 2019
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RBRC No. RBRC09602  
Type TransgeneCartagena  
Species Mus musculus  
Strain name B6.FVB-Tg(CD2-Ccdc86)1Hfuj  
Former Common name Cyclon-Tg(B)  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Hodaka Fujii, New York University in 2009. A DNA construct was injected to fertilized eggs derived from FVB/N. Mice were backcrossed to C57BL/6 background for at least 6 generations.  
Strain description Transgenic mouse line expressing mouse Ccdc86 (coiled-coil domain containing 86, Cyclon) under the control of human CD2 promoter. Both T and B lymphocytes express transgene. Tg mice exhibited elevation of Fas expression in activated T lyphocytes.  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Ccdc86  
Symbol name coiled-coil domain containing 86  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References No Data  
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Regulation of Fas-mediated immune homeostasis by an activation-induced protein, Cyclon. Saint Fleur S, Hoshino A, Kondo K, Egawa T, Fujii H. Blood (2009) 114 (7): 1355-65. The BIOLOGICAL RESOURCE shall be used only for academic research purposes by not-for-profit institutions. Use of the BIOLOGICAL RESOURCE by for-profit institutions or use for commercial research purposes shall require a commercial license from the Depositor. A recipient shall also acquire a prior written consent from the Depositor prior to filing an application for a patent, or intellectual property or other rights based on the results of their use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
Depositor Fujii, Hodaka (New York University Medical Center)  Fujii, Hodaka 
Strain Status /
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