Strain Data Sheet
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC09665  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6(CB)-Gt(ROSA)26Sor<tm1.1(CAG-AKR1C3)Watk>  
Former Common name hPGFS KI  
H-2 Haplotype No Data  
ES cell line RENKA [C57BL/6NCrlCrlj]  
Background strain No Data  
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Kikuko Watanabe, Koshien University in 2015. RENKA ES cell line (C57BL/6N) was used. Mice were maintained in C57BL/6 and CBA mixed background.  
Strain description Knock-in mice for overexpression of human AKR1C3. Targeted insertion of CAG-loxP-CAT-FRT-PGK-neo-FRT-loxP-FAM213B-pA cassette into the mouse Rosa26 locus.  A DNA fragment of loxP-CAT-FRT-PGK-neo-FRT-loxP was removed by crossing to B6;CBA-Tg(CAG-Cre)47Imeg.  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Gt(ROSA)26Sor  
Symbol name gene trap ROSA 26, Philippe Soriano  
Chromosome 6  
Common name No Data  
Symbol description No Data  
Promoter CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)  
 2 Symbol AKR1C3  
Symbol name No Data  
Chromosome 6  
Common name No Data  
Symbol description No Data  
References No Data  
Research applications Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
FEBS lett., 462, 335-340 (1999).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the Dr. Kikuko Watanabe is requested.  
Additional information
 1 No Data  
Depositor Watanabe, Kikuko (Kansai Medical University)  Watanabe, Kikuko 
Strain Status /
(Expected delivery)

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