Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
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RBRC No. RBRC09695  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.Cg-Rnf31<tm1.2Kiwa>  
Former Common name HOIP delta linear mice  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Kazuhiro Iwai, Graduate School of Medicine, Kyoto University. TT2 ES cell line [(C57BL/6 x CBA)F1] was used. A pair of loxP sites were flanking an exon encoding RING-IBR-RING domain, and a genomic fragment between loxP sites were deleted by CAG-Cre. A Neo resistance gene was also deleted. C57BL/6 congenic strain.  
Strain description Rnf31 (ring finger protein 31, HOIP) deficient mice. Exon encoding a RING-IBR-RING domain was deleted. Homozygous mutants are lethal at embryonic day 10.5.  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Rnf31  
Symbol name ring finger protein 31  
Chromosome 14  
Common name No Data  
Symbol description No Data  
 2 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 14  
Common name No Data  
Symbol description No Data  
References No Data  
Research applications Cell Biology Research,
Cre/loxP system,
Immunology and Inflammation Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Mol. Cell Biol., 36, 1569-1583 (2016).
The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Iwai, Kazuhiro (Kyoto University)  Iwai, Kazuhiro 
Strain Status /
Availability
(Expected delivery)

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