Strain Data Sheet
Data update: Aug 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC09703  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129-Mta2<tm1Nkcc>  
Former Common name Mta2 KO  
H-2 Haplotype No Data  
ES cell line E14TG2a [129P2/OlaHsd]carries Hprt  
Background strain No Data  
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Soichi Takiguchi, National Hospital Organization Kyushu Cancer Center, in collaboration with Graduate School of Pharmaceutical Sciences, The University of Tokyo in 2002. E14TG2aIV ES cell line (129P2/OlaHsd) was used. C57BL/6J congenic strain (backcrossed to C57BL/6J for 12 generations).  
Strain description Mta2 (metastasis-associated gene family, member 2) knockout mice. A genomic fragment corresponding from exon 8 to exon 12 of the Mta2 gene was replaced with a Neo resistance gene. The rate of homozygous mutants born from hetero x hetero crossing is much lower than what is expected from the Mendel's law of inheritance.  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Mta2  
Symbol name metastasis-associated gene family, member 2  
Chromosome 19  
Common name No Data  
Symbol description No Data  
Promoter mouse RNA polymerase II promoter (PolII promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 19  
Common name No Data  
Symbol description No Data  
References No Data  
Research applications Cancer Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use or publication with the results from the use of the BIOLOGICAL RESOURCE. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. However, it may not be a collaboration if the research interest is out of field of the DEPOSITOR.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Takiguchi, Soichi (National Kyushu Cancer Center)  Takiguchi, Soichi 
Strain Status /
(Expected delivery)

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