Strain Data Sheet

RBRC09741

Strain Information

Image
BRC No.RBRC09741
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB6.C3-Hps4<le>/Gku
Former Common name
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJmsSlc
Appearance
Strain developmentDeveloped by Go Kuratomi, Dokkyo Medical University in 2014. B6.C3-Pde6brd1Hps4le/J (Stock number:000002) were intercrossed each other to segregate Pde6brd1 and Hps4le. B6 congenic strain.
Strain descriptionLight-ear (le) is a spontaneous mutation in Hps4 (Hermansky-Pudlak syndrome 4 homolog (human)). Retinal degeneration 1 (Pde6brd1) was corrected in this B6-congenic strain
Colony maintenance
ReferencesBMC Psychiatry. 2013 Oct 30;13:276. doi: 10.1186/1471-244X-13-276. 24168225
Nature Genetics, 30, 321-324 (2002). 11836498

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Hps4Hermansky-Pudlak syndrome 45Hps4<le>light-ear

Ordering Information

Donor DNA
Research applicationDermatology Research
Mouse Models for Human Disease
Sensorineural Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.)
DepositorGo Kuratomi (Dokkyo Medical University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data