Strain Data Sheet
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC09759  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129P2-Chd8<tm2.1Kei>  
Former Common name Chd8L KO  
H-2 Haplotype No Data  
ES cell line E14 [129P2/OlaHsd]  
Background strain C57BL/6JJcl  
 1 Appearance No Data  
Genotype No Data  
Strain development Deposited by Keiichi Nakayama, Medical Institute of Bioregulation, Kyusyu University in 2016. E14(129P2/OlaHsd) ES cell line was used. C57BL/6 congenic strain.  
Strain description Chd8l (chromodomain helicase DNA binding protein 8 long isoform) knockout mice. Homozygous mutants are lethal. A pair of loxP sites with a neo gene cassette flanking exons 11 to 13, and then these exons were deleted by Cre expression in ES cells. Mouse strain carrying deletion of both long isoform (Chd8l) and short isoform (Chd8s) is available as RBRC09758.  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Chd8  
Symbol name chromodomain helicase DNA binding protein 8  
Chromosome 14  
Common name No Data  
Symbol description No Data  
 2 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 14  
Common name No Data  
Symbol description No Data  
References No Data  
Research applications Cre/loxP system,
Mouse Models for Human Disease  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.  
Additional information
 1 Mouse of the Month Nov 2018  
 2 Genotyping protocol <PCR>  
Depositor Nakayama, Keiichi (Medical institute of bioregulation, Kyushu University)  Nakayama, Keiichi 
Strain Status /
(Expected delivery)

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