Strain Data Sheet
Data update: Jul 19, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC09804  
Type TransgeneCartagena  
Species Mus musculus  
Strain name B6;B6D2-Tg(Myh6-HK2)AChuan  
Former Common name No Data  
H-2 Haplotype No Data  
Background strain No Data  
 1 Appearance No Data  
Genotype No Data  
Strain description Hexokinase 2, which phosphorylates glucose to form G6P, is a key enzyme in glucose metabolism. A growing body of evidence has shown that HK2 is involved in cardioprotection. These transgenic mice overexpress human HK2 in the heart muscle and have no obvious abnormality. It was reported that cardiac overexpression of mouse HK2 attenuated hypertrophy by increasing pentose phosphate pathway.  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol GH  
Symbol name Growh hormone polyA (human)  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
Promoter Rat Myh6 promoter  
 2 Symbol HK2  
Symbol name Hexokinase 2 (human)  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References No Data  
Research applications Cardiovascular Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT agrees to use the BIOLOGICAL RESOURSE only for publication of research papers. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
Depositor Iwamoto, Takashi (Chubu University)  Iwamoto, Takashi 
Strain Status /
(Expected delivery)

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