Strain Information | |
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Image | |
BRC No. | RBRC09914 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-Drd2<tm1.1Mmsh> |
Former Common name | Drd2 floxed, B6-Drd2 floxed, fDrd2 |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | |
Appearance | |
Strain development | Developed by Noboru Mizushima, The University of Tokyo. RENKA ES cells derived from C57BL/6N was used and mice were maintained by brother-sister mating. A neo cassette was removed by crossing with B6-Tg(CAG-FLPe)36. |
Strain description | Floxed Drd2 mice. Exon 2 of Drd2 is flanked by loxP sites. Conditional Drd2 deficient mice can be generated by crossing with cell type-specific Cre driver mice. |
Colony maintenance | |
References | Sci. Rep., 4:3976 (2014). 24496082 |
Health Report | |
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Examination Date / Room / Rack | 2024/02/26Room:4-CRack:D 2023/11/27Room:4-CRack:D 2023/08/28Room:4-CRack:D 2023/05/29Room:4-CRack:D 2023/02/27Room:4-CRack:D 2022/11/29Room:4-CRack:D 2022/08/29Room:4-CRack:D 2022/05/31Room:4-CRack:D |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site9Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP9loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP9loxP |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, yeast FRT (flipase recombination target) site, mouse Drd2 genomic DNA |
Research application | Cre/loxP system FLP/frt system Neurobiology Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR during first TWO years after deposition by the DEPOSITOR to the RIKEN BRC. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Masayoshi Mishina (Ritsumeikan University) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) Live mouse (3 to 6 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |