Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jul 19, 2019
Health Report   PCR Protocol   Thawing Method
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  Mouse Marking
Figure
  Order
RBRC No. RBRC10238  
Type Targeted Mutation CongenicCartagena  
Species Mus musculus  
Strain name B6;Cg-Tg(Cryd1/Cryaa-Sfrp2)1Jmca  
Former Common name Sfrp2 lens (M2)  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Transgenic construct was injected into BCBF1 (C57/BL6xCBA) embryos.
Generated by John McAvoy laboratory in the University of Sydney.
After backcrossing to C57/BL6 line for a few generations, the line has been maintained as inbred.
Small lens formation. Cataract development.Mice can be maintained as heterozygous or homozygous.  
Strain description Transgenic mouse line with Sfrp2 (secreted frizzled related protein-2) overexpression in lens.  
Health Report
Gene Details
Promoter No Data  
 1 Symbol GH  
Symbol name Human growth hormone poly A  
Chromosome UN  
Common name No Data  
Symbol description No Data  
Promoter Chicken delta 1-crystallin (ASL1) enhancer and promoter, Mouse alpha A-crystallin (Cryaa) promoter, Rabbit beta-globin intron  
 2 Symbol Sfrp2  
Symbol name secreted frizzled-related protein 2  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References No Data  
Research applications Developmental Biology Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Development Biology, 324, 161-176 (2008).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
For use of the BIOLOGICAL RESOURCE by a for-profit organization, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
Depositor Sugiyama, Yuki (Okinawa Institute of Science and Technology Graduate University)  Sugiyama, Yuki 
Strain Status /
Availability
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