Strain Information | |
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Image | |
BRC No. | RBRC10242 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129-Scn1a<tm2.1Kzy> |
Former Common name | |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | Developed by Ikuo Ogiwara and Kazuhiro Yamakawa, RIKEN BSI in 2007. E14 ES cells(129P2/OlaHsd) were used and the Neo gene was deleted by CAG-Flpe mice. C57BL/6J congenic line. |
Strain description | Floxed mice for the Scn1a (sodium channel, voltage-gated, type I, alpha) gene. A pair of loxP sites flank Exon 7 of the Scn1a. |
Colony maintenance | |
References | Human Molecular Genetics, 22(23), 4784-4804 (2013). 23922229 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Scn1asodium channel, voltage-gated, type I, alpha2Scn1a<tm2.1Kzy>targeted mutation 2.1, Kazuhiro Yamakawa Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site2Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP2loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP2loxP |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, S.cerevisiae FRT(flipase recombination target) site, mouse Scn1a genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Human Molecular Genetics, 22(23), 4784-4804 (2013).The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Kazuhiro Yamakawa (RIKEN) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |