Strain Information | |
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Image | |
BRC No. | RBRC10382 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Arf6<tm2.1Yaka> |
Former Common name | Arf6-flox |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Yasunori Kanaho and Tunaki Hongu, University of Tsukuba in 2008. TT2 ES cells dereived from (C57BL/6NCrlj x CBA/JNCrlj)F1 was used, and then mice were backcrossed to C57BL/6J for more than 10 generations. |
Strain description | Arf6 floxed mice. A pair of loxP sites flank Exon 1 and 2 of the Arf6 gene. Homozygous floxed mice show no gross abnormality. |
Colony maintenance | |
References | Sci. Rep., 7, 46649 (2017). 28429746 Nat. Commun., 6, 7925 (2015). 26239146 Nat. Commun., 5, 4744 (2014). 25144208 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site12Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP12loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP12loxP |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, yeast(S.crevisiae) FRT (flippase recombination target) site, mouse Arf6 genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Commun., 5, 4744 (2014). Nat. Commun., 6, 7925 (2015). Sci. Rep., 7, 46649 (2017).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. |
Depositor | Yasunori Kanaho (University of Tsukuba) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |