Strain Information | |
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Image | |
BRC No. | RBRC10428 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Xkr8<tm1.1Osa> |
Former Common name | Xkr8 flox/flox |
H-2 Haplotype | |
ES Cell line | Bruce 4 [B6.Cg-Thy1<a>] |
Background strain | |
Appearance | |
Strain development | Developed by Shigekazu Ngata and Jun Suzuki at Osaka University in 2013. Bruce 4 ES cell line was used. A pair of loxP flanks Exon 3 of the Xkr8 gene. Neomycin resistance gene was removed by crossing CAG-Flp mice. |
Strain description | Xkr8 (X-linked Kx blood group related 8) floxed mice. |
Colony maintenance | |
References | Science, 341, 403-406 (2013). 23845944 Proc. Natl. Acad. Sci. USA, 115(9):2132-2137 (2018). 29440417 |
Health Report | |
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Examination Date / Room / Rack | 2023/04/10Room:3-BRack:G 2023/01/10Room:3-BRack:G 2022/10/11Room:3-BRack:G 2022/07/11Room:3-BRack:G |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site4Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP4loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP4loxP |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, yeast FRT (flippase recombination target) site, mouse Xkr8 genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science, 341, 403-406 (2013).The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Shigekazu Nagata (Osaka University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |