Strain Information | |
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Image | |
BRC No. | RBRC10464 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129S4-Cenpu<tm2.1Tfw>/Yuwa |
Former Common name | Cenp50floxB6 |
H-2 Haplotype | |
ES Cell line | J1 [129S4/SvJae] |
Background strain | |
Appearance | |
Strain development | Developed by Tatsuo Fukagawa, Osaka University, and deposited by Yuichi Wakabayashi, Chiba Cancer Center, in 2018. ES cells derived from 129/Sv were used and then mice were further backcrossed to C57BL/6J for more than 20 generations. C57BL/6J congenic strain. Y choromosome is from C57BL/6J. |
Strain description | Cenpu (centromere protein U, Cenp50) floxed mice. Homozygous null mutants are embryonically lethal. A pair of loxP flanks Exon 4, 5 and 6 of the Cenpu gene. |
Colony maintenance | |
References | Chromosome Res., 22(3):293-303 (2014). 24481920 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site8Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP8loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP8loxP |
Ordering Information | |
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Donor DNA | Phage P1 loxP sites, yeast FRT (flippase recombination target) site, mouse Cenpu genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Yuichi Wakabayashi (Chiba Cancer Center) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |