Strain Information | |
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Image | |
BRC No. | RBRC10599 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6J-Tg(Slc6a4-GAP/GFP)1Ito |
Former Common name | 5HTT-GAP43-EGFP, TCA-GFP, Sert-GAP43-EGFP |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Deposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. A BAC DNA construct was injected to fertilized eggs derived from C57BL/6J. Mice were maintained by crossing to C57BL/6J. C57BL/6 genetic background. |
Strain description | A BAC transgenic mouse in which GAP/GFP is under the control of the Slc6a4 (solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; 5Htt) gene promoter. |
Colony maintenance | |
References | Neuron, 82(2) 365-79 (2014). 24685175 |
Health Report | |
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Examination Date / Room / Rack | 2024/03/11Room:3-5Rack:C 2023/12/11Room:3-5Rack:C 2023/09/11Room:3-5Rack:C 2023/06/13Room:3-5Rack:C 2023/05/22Room:3-5Rack:C 2023/03/13Room:3-5Rack:C |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EGFPEnhanced Green Fluorescent Protein (Aequorea victoria)UNEGFP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) siteUNFrt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GAP43growth associated protein 43UNGAP43 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40UN |
Ordering Information | |
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Donor DNA | mouse serotonin transporter(5HTTP) genomic DNA, GAP43 palmitoylation signal, jellyfish EGFP cDNA, SV40 polyA, yeast FRT (flippase recombination target) site, Phage P1 loxP site derived from pBACe3.6 vector |
Research application | Cre/loxP system FLP/frt system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mizuno et al. Neuron, 82(2) 365-79 (2014). |
Depositor | Shigeyoshi Itohara (RIKEN CBS) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |