Strain Information | |
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Image | |
BRC No. | RBRC10054 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Aqp4<tm1Tsna> |
Former Common name | AQP4 Neo, Aqp4 flox |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | C57BL/6NCrl |
Appearance | |
Strain development | Developed by Mika Tsujita, Brain Research Institute, Niigata University. RENKA ES cells derived from C57BL/6 were used. C57BL/6 genetic background. |
Strain description | Aqp4 mutant mice in which loxP-FRT-pgk-neo-FRT DNA fragment was inserted between exon 1 and exon 2, and another loxP was inserted between exon 3 and exon 4. |
Colony maintenance | |
References | Neurosci. Res., 64, 208-212 (2009). 19428702 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site18Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site18Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)18mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 PolyA signal18 |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, Saccharomyces cerevisiae FRT sites, mouse Pgk1 promoter, E. coli aminoglycoside 3'-phosphotransferase, Simian virus 40 SV40 pA, mouse Aqp4 genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Neurosci. Res., 64, 208-212 (2009). |
Depositor | Mika Terumitsu-Tsujita (Niigata University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Mouse of the Month Sep 2017 Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |