Strain Information | |
---|---|
Image | |
BRC No. | RBRC10896 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129P2-Mapk1<tm2.1Moga> |
Former Common name | ERK2 flox |
H-2 Haplotype | |
ES Cell line | EB3 [129/Ola] |
Background strain | |
Appearance | |
Strain development | A floxed mutant mice possess loxP sites flanking the ERK2 gene established by M. Ogata, et al., in 2003. This strain may be useful for generating conditional mutations of ERK2. C57BL/6 congenic strain by backcrossing over 8 generations. |
Strain description | ERK2 flox strain. A pair of loxP flanks exon 3 of the Mapk1 gene. |
Colony maintenance | |
References | Immunity, 28(4):499-508 (2008). 18356083 Genes Cells, 8(11):847-56 (2003). 14622137 |
Health Report | |
---|---|
Examination Date / Room / Rack | 2022/06/13Room:3-6Rack:C |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Mapk1mitogen-activated protein kinase 116Mapk1<tm2.1Moga>targeted mutation 2.1, Masato Ogata9030612K14Rik, Erk2, MAPK2, p42mapk, Prkm1 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP16loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP16loxP |
Ordering Information | |
---|---|
Donor DNA | Bacteriophage Pl loxP sites, Mouse Mapk1 genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes to Cells. 8, 847-856 (2003). Immunity, 28(4):499-508 (2008).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Masato Ogata (Mie University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |